Algeria Angola Argentina Australia Bahrain Bangladesh Botswana Brazil Cameroon Canada Chile China Colombia Congo, Dem Rep of Cote d'Ivoire Egypt Ethiopia France Gabon Germany Ghana Hong Kong India Indonesia Iraq Ireland Italy Japan Jordan Kenya Kuwait

Lebanon Libya Macao Malaysia Mali Mauritius Mexico Morocco Mozambique Namibia Netherlands New Zealand Nigeria Oman Pakistan Palestine Philippines Poland Portugal Qatar Rwanda Saudi Arabia Senegal Singapore South Africa South Korea Spain Sri Lanka Sudan Sweden Switzerland Taiwan Tanzania Thailand Tunisia Turkey Uganda United Arab Emirates United Kingdom United States Vietnam Zambia Zimbabwe العربية English

Flight Schedules

Last Updated: Fri, 2 May, 2025

Time Earliest
- Earliest
- Latest
Depart Earliest
- Earliest
- Latest
Arrive
- Earliest
- Latest
Duration
- Shortest
- Longest
Stopover
All
Airline Filter by Airline
View All Airline
Availability
- M
- T
- W
- T
- F
- S
- S

08:25 GUA

13:59 SDQ

3Hrs, 34m Direct
GUAGuatemala City Airport 08:25 - SDQ 13:59 3h 34m Direct
GUAGuatemala City Airport 08:25
SDQSanto Domingo Las Americas Airport 13:59
3h 34m
Direct
Arajet (DM 4601)Boeing 737 Max 8 Passenger
Arajet (DM 4601)
- -
- -
- -
- T
- -
- S
- -
Boeing 737 Max 8 Passenger

08:45 GUA

14:19 SDQ

3Hrs, 34m Direct
GUAGuatemala City Airport 08:45 - SDQ 14:19 3h 34m Direct
GUAGuatemala City Airport 08:45
SDQSanto Domingo Las Americas Airport 14:19
3h 34m
Direct
Arajet (DM 4601)Boeing 737 Max 8 Passenger
Arajet (DM 4601)
- M
- -
- W
- -
- -
- -
- -
Boeing 737 Max 8 Passenger

04:23 GUA

13:10 SDQ

6Hrs, 47m 1 Stop (PTY)
GUAGuatemala City Airport 04:23 - SDQ 13:10 6h 47m 1 Stop (PTY) Panama City
GUAGuatemala City Airport 04:23

PTYPanama City Tocumen International Airport 09:37
PTYPanama City Tocumen International Airport 07:50

SDQSanto Domingo Las Americas Airport 13:10
6h 47m (1h 47m)
1 Stop PTY · Panama City 1h 47m
Copa Airlines (CM 407)Boeing 737 800

Copa Airlines (CM 298)Boeing 737 800
Copa Airlines (CM 407)
- M
- T
- W
- T
- -
- S
- S

04:23 GUA

16:17 SDQ

9Hrs, 54m 1 Stop (PTY)
GUAGuatemala City Airport 04:23 - SDQ 16:17 9h 54m 1 Stop (PTY) Panama City
GUAGuatemala City Airport 04:23

PTYPanama City Tocumen International Airport 12:44
PTYPanama City Tocumen International Airport 07:50

SDQSanto Domingo Las Americas Airport 16:17
9h 54m (4h 54m)
1 Stop PTY · Panama City 4h 54m
Copa Airlines (CM 407)Boeing 737 800

Copa Airlines (CM 128)Boeing 737 Max 9 Passenger
Copa Airlines (CM 407)
- M
- -
- -
- -
- -
- -
- -

04:23 GUA

16:17 SDQ

9Hrs, 54m 1 Stop (PTY)
GUAGuatemala City Airport 04:23 - SDQ 16:17 9h 54m 1 Stop (PTY) Panama City
GUAGuatemala City Airport 04:23

PTYPanama City Tocumen International Airport 12:44
PTYPanama City Tocumen International Airport 07:50

SDQSanto Domingo Las Americas Airport 16:17
9h 54m (4h 54m)
1 Stop PTY · Panama City 4h 54m
Copa Airlines (CM 407)Boeing 737 800

Copa Airlines (CM 128)Boeing 737 800
Copa Airlines (CM 407)
- -
- T
- -
- T
- F
- S
- S

04:23 GUA

13:10 SDQ

6Hrs, 47m 1 Stop (PTY)
GUAGuatemala City Airport 04:23 - SDQ 13:10 6h 47m 1 Stop (PTY) Panama City
GUAGuatemala City Airport 04:23

PTYPanama City Tocumen International Airport 09:37
PTYPanama City Tocumen International Airport 07:50

SDQSanto Domingo Las Americas Airport 13:10
6h 47m (1h 47m)
1 Stop PTY · Panama City 1h 47m
Copa Airlines (CM 407)Boeing 737 800

Copa Airlines (CM 298)Boeing 737 Max 9 Passenger
Copa Airlines (CM 407)
- -
- -
- -
- -
- F
- -
- -

05:39 GUA

16:17 SDQ

8Hrs, 38m 1 Stop (PTY)
GUAGuatemala City Airport 05:39 - SDQ 16:17 8h 38m 1 Stop (PTY) Panama City
GUAGuatemala City Airport 05:39

PTYPanama City Tocumen International Airport 12:44
PTYPanama City Tocumen International Airport 10:32

SDQSanto Domingo Las Americas Airport 16:17
8h 38m (2h 12m)
1 Stop PTY · Panama City 2h 12m
Copa Airlines (CM 392)Boeing 737 800

Copa Airlines (CM 128)Boeing 737 Max 9 Passenger
Copa Airlines (CM 392)
- M
- -
- -
- -
- -
- -
- -

05:39 GUA

16:17 SDQ

8Hrs, 38m 1 Stop (PTY)
GUAGuatemala City Airport 05:39 - SDQ 16:17 8h 38m 1 Stop (PTY) Panama City
GUAGuatemala City Airport 05:39

PTYPanama City Tocumen International Airport 12:44
PTYPanama City Tocumen International Airport 10:32

SDQSanto Domingo Las Americas Airport 16:17
8h 38m (2h 12m)
1 Stop PTY · Panama City 2h 12m
Copa Airlines (CM 392)Boeing 737 800

Copa Airlines (CM 128)Boeing 737 800
Copa Airlines (CM 392)
- -
- T
- -
- T
- F
- S
- S

06:35 GUA

17:15 SDQ

8Hrs, 40m 1 Stop (BOG)
GUAGuatemala City Airport 06:35 - SDQ 17:15 8h 40m 1 Stop (BOG) Bogota
GUAGuatemala City Airport 06:35

BOGBogota Airport 13:35
BOGBogota Airport 10:50

SDQSanto Domingo Las Americas Airport 17:15
8h 40m (2h 45m)
1 Stop BOG · Bogota 2h 45m
Avianca (AV 165)Airbus

Avianca (AV 250)Airbus
Avianca (AV 165)
- -
- T
- -
- T
- -
- S
- -

07:09 GUA

16:17 SDQ

7Hrs, 08m 1 Stop (PTY)
GUAGuatemala City Airport 07:09 - SDQ 16:17 7h 08m 1 Stop (PTY) Panama City
GUAGuatemala City Airport 07:09

PTYPanama City Tocumen International Airport 12:44
PTYPanama City Tocumen International Airport 10:36

SDQSanto Domingo Las Americas Airport 16:17
7h 08m (2h 08m)
1 Stop PTY · Panama City 2h 08m
Copa Airlines (CM 389)Boeing 737 800

Copa Airlines (CM 128)Boeing 737 800
Copa Airlines (CM 389)
- -
- T
- -
- T
- F
- -
- S

07:09 GUA

16:17 SDQ

7Hrs, 08m 1 Stop (PTY)
GUAGuatemala City Airport 07:09 - SDQ 16:17 7h 08m 1 Stop (PTY) Panama City
GUAGuatemala City Airport 07:09

PTYPanama City Tocumen International Airport 12:44
PTYPanama City Tocumen International Airport 10:36

SDQSanto Domingo Las Americas Airport 16:17
7h 08m (2h 08m)
1 Stop PTY · Panama City 2h 08m
Copa Airlines (CM 389)Boeing 737 800

Copa Airlines (CM 128)Boeing 737 Max 9 Passenger
Copa Airlines (CM 389)
- M
- -
- -
- -
- -
- -
- -

07:09 GUA

16:17 SDQ

7Hrs, 08m 1 Stop (PTY)
GUAGuatemala City Airport 07:09 - SDQ 16:17 7h 08m 1 Stop (PTY) Panama City
GUAGuatemala City Airport 07:09

PTYPanama City Tocumen International Airport 12:44
PTYPanama City Tocumen International Airport 10:36

SDQSanto Domingo Las Americas Airport 16:17
7h 08m (2h 08m)
1 Stop PTY · Panama City 2h 08m
Copa Airlines (CM 389)Boeing 737 Max 8 Passenger

Copa Airlines (CM 128)Boeing 737 800
Copa Airlines (CM 389)
- -
- -
- -
- -
- -
- S
- -

10:23 GUA

22:08 SDQ

9Hrs, 45m 1 Stop (PTY)
GUAGuatemala City Airport 10:23 - SDQ 22:08 9h 45m 1 Stop (PTY) Panama City
GUAGuatemala City Airport 10:23

PTYPanama City Tocumen International Airport 18:36
PTYPanama City Tocumen International Airport 13:49

SDQSanto Domingo Las Americas Airport 22:08
9h 45m (4h 47m)
1 Stop PTY · Panama City 4h 47m
Copa Airlines (CM 111)Boeing 737 800

Copa Airlines (CM 268)Boeing 737 800
Copa Airlines (CM 111)
- M
- -
- -
- -
- -
- -
- -

10:23 GUA

22:08 SDQ

9Hrs, 45m 1 Stop (PTY)
GUAGuatemala City Airport 10:23 - SDQ 22:08 9h 45m 1 Stop (PTY) Panama City
GUAGuatemala City Airport 10:23

PTYPanama City Tocumen International Airport 18:36
PTYPanama City Tocumen International Airport 13:49

SDQSanto Domingo Las Americas Airport 22:08
9h 45m (4h 47m)
1 Stop PTY · Panama City 4h 47m
Copa Airlines (CM 111)Boeing 737 700

Copa Airlines (CM 268)Boeing 737 800
Copa Airlines (CM 111)
- -
- T
- W
- T
- F
- S
- S

12:45 GUA

22:40 SDQ

7Hrs, 55m 1 Stop (MIA)
GUAGuatemala City Airport 12:45 - SDQ 22:40 7h 55m 1 Stop (MIA) Miami
GUAGuatemala City Airport 12:45

MIAMiami International Airport 20:25
MIAMiami International Airport 17:30

SDQSanto Domingo Las Americas Airport 22:40
7h 55m (2h 55m)
1 Stop MIA · Miami 2h 55m
American Airlines (AA 1006)Boeing 737 Max 8 Passenger

American Airlines (AA 2123)Boeing 737 800
American Airlines (AA 1006)
- M
- T
- W
- T
- F
- S
- S

13:12 GUA

22:08 SDQ

6Hrs, 56m 1 Stop (PTY)
GUAGuatemala City Airport 13:12 - SDQ 22:08 6h 56m 1 Stop (PTY) Panama City
GUAGuatemala City Airport 13:12

PTYPanama City Tocumen International Airport 18:36
PTYPanama City Tocumen International Airport 16:39

SDQSanto Domingo Las Americas Airport 22:08
6h 56m (1h 57m)
1 Stop PTY · Panama City 1h 57m
Copa Airlines (CM 384)Boeing 737 800

Copa Airlines (CM 268)Boeing 737 800
Copa Airlines (CM 384)
- M
- T
- W
- T
- F
- S
- -

13:12 GUA

22:08 SDQ

6Hrs, 56m 1 Stop (PTY)
GUAGuatemala City Airport 13:12 - SDQ 22:08 6h 56m 1 Stop (PTY) Panama City
GUAGuatemala City Airport 13:12

PTYPanama City Tocumen International Airport 18:36
PTYPanama City Tocumen International Airport 16:39

SDQSanto Domingo Las Americas Airport 22:08
6h 56m (1h 57m)
1 Stop PTY · Panama City 1h 57m
Copa Airlines (CM 384)Boeing 737 700

Copa Airlines (CM 268)Boeing 737 800
Copa Airlines (CM 384)
- -
- -
- -
- -
- -
- -
- S

16:23 GUA

02:45 SDQ

8Hrs, 22m 1 Stop (PTY)
GUAGuatemala City Airport 16:23 - SDQ 02:45 8h 22m 1 Stop (PTY) Panama City
GUAGuatemala City Airport 16:23

PTYPanama City Tocumen International Airport 23:13
PTYPanama City Tocumen International Airport 19:50

SDQSanto Domingo Las Americas Airport 02:45
8h 22m (3h 23m)
1 Stop PTY · Panama City 3h 23m
Copa Airlines (CM 361)Boeing 737 Max 9 Passenger

Copa Airlines (CM 107)Boeing 737 700
Copa Airlines (CM 361)
- -
- -
- -
- -
- -
- S
- -

16:23 GUA

02:45 SDQ

8Hrs, 22m 1 Stop (PTY)
GUAGuatemala City Airport 16:23 - SDQ 02:45 8h 22m 1 Stop (PTY) Panama City
GUAGuatemala City Airport 16:23

PTYPanama City Tocumen International Airport 23:13
PTYPanama City Tocumen International Airport 19:50

SDQSanto Domingo Las Americas Airport 02:45
8h 22m (3h 23m)
1 Stop PTY · Panama City 3h 23m
Copa Airlines (CM 361)Boeing 737 Max 9 Passenger

Copa Airlines (CM 107)Boeing 737 800
Copa Airlines (CM 361)
- -
- -
- -
- -
- F
- -
- -

16:23 GUA

02:45 SDQ

8Hrs, 22m 1 Stop (PTY)
GUAGuatemala City Airport 16:23 - SDQ 02:45 8h 22m 1 Stop (PTY) Panama City
GUAGuatemala City Airport 16:23

PTYPanama City Tocumen International Airport 23:13
PTYPanama City Tocumen International Airport 19:50

SDQSanto Domingo Las Americas Airport 02:45
8h 22m (3h 23m)
1 Stop PTY · Panama City 3h 23m
Copa Airlines (CM 361)Boeing 737 700

Copa Airlines (CM 107)Boeing 737 700
Copa Airlines (CM 361)
- M
- -
- W
- -
- -
- -
- -

Sorry, there are no schedules matching your filters. Try removing one. reset

What’s the fastest flight time from Guatemala to Santo Domingo?

The fastest flight time for direct flights from Guatemala to Santo Domingo is 3 hours 34 minutes. Check latest flight schedules & prices on Wego.

How far is Santo Domingo from Guatemala?

The flight distance between Guatemala and Santo Domingo is 2233km. Check all available flights on Wego.

When is the earliest and latest flight of the day?

The earliest flight of the day departs at 04:23. The last flight of the day departs at 04:23. See the full list of flight times on Wego.

How many airlines offer direct flights from Guatemala to Santo Domingo?

There are 1 airlines that offer direct flights from Guatemala to Santo Domingo. Find out the list of airlines on Wego.

Popular Destinations From Santo Domingo

Popular Destinations From Guatemala

Popular Hotels in Santo Domingo

Hotels In Popular Destinations

Wego searches for the best deals on these sites & many more